Constantinos Mikelis Selected Research

pleiotrophin (HARP)

7/2013	Expression of the growth factor pleiotrophin and its receptor protein tyrosine phosphatase beta/zeta in the serum, cartilage and subchondral bone of patients with osteoarthritis.
1/2013	Interplay between αvβ3 integrin and nucleolin regulates human endothelial and glioma cell migration.
6/2011	A peptide corresponding to the C-terminal region of pleiotrophin inhibits angiogenesis in vivo and in vitro.
12/2009	Roles of pleiotrophin in tumor growth and angiogenesis.
4/2009	Nitric oxide stimulates migration of human endothelial and prostate cancer cells through up-regulation of pleiotrophin expression and its receptor protein tyrosine phosphatase beta/zeta.
1/2008	Heparin-binding protein pleiotrophin: an important player in the angiogenic process.
1/2008	Heparin affin regulatory peptide/pleiotrophin negatively affects diverse biological activities in C6 glioma cells.
6/2007	Pleiotrophin as a possible new target for angiogenesis-related diseases and cancer.

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Constantinos Mikelis Research Topics

Disease

9	Neoplasms (Cancer) 06/2017 - 06/2007
3	Glioma (Gliomas) 01/2013 - 01/2008
1	Pancreatic Neoplasms (Pancreatic Cancer) 06/2017
1	Osteoarthritis 07/2013
1	Nervous System Neoplasms (Neoplasms, Nervous System) 12/2009
1	Prostatic Neoplasms (Prostate Cancer) 04/2009
1	Hemorrhage 01/2009

Drug/Important Bio-Agent (IBA)

8	pleiotrophin (HARP)IBA 07/2013 - 06/2007
5	Intercellular Signaling Peptides and Proteins (Growth Factors)IBA 07/2013 - 04/2009
4	Biological ProductsIBA 01/2016 - 06/2007
3	Class 5 Receptor-Like Protein Tyrosine PhosphatasesIBA 07/2013 - 04/2009
2	Heparin (Liquaemin)FDA LinkGeneric 06/2011 - 12/2009
1	Inositol (Myoinositol)IBA 06/2017
1	Carrier Proteins (Binding Protein)IBA 06/2017
1	Penfluridol (Semap)IBA 06/2017
1	Transcription Factor CHOPIBA 06/2017
1	Pharmaceutical PreparationsIBA 01/2016
1	Proteins (Proteins, Gene)FDA Link 01/2013
1	IntegrinsIBA 01/2013
1	NucleolinIBA 01/2013
1	Nitric Oxide Synthase Type III (Endothelial Nitric Oxide Synthase)IBA 04/2009
1	Nitric Oxide (Nitrogen Monoxide)FDA Link 04/2009
1	Protease Inhibitors (Protease Inhibitor)IBA 01/2009
1	Fibrinolysin FDA Link 01/2009
1	Aprotinin (Trasylol)FDA Link 01/2009
1	Vascular Endothelial Growth Factor Receptors (VEGF Receptors)IBA 01/2008
1	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 01/2008

Therapy/Procedure

1	Drug Therapy (Chemotherapy) 06/2017
1	Aftercare (After-Treatment) 06/2017